我领导肿瘤学R&D and am responsible for our 肿瘤学 portfolio from discovery through to late-stage development.

I have over 20  years’ experience in drug discovery and development with a background as a Clinical Oncologist. I trained in medicine at Manchester and 剑桥 Universities, was admitted to the Royal College of Physicians in 1992, and then trained in Clinical 肿瘤学 in London. I gained a Fellowship of the Royal College of Radiologists in 1997 and completed a PhD at the University of London involving translational work on a vascular-targeting agent. In 2017, I was awarded an honorary Doctorate of Medical Science from the Institute of Cancer Research, and in 2018 I was admitted to the Fellowship of the Academy of Medical Sciences. 

I moved from medicine to industry in 2001, to Bristol-Myers Squibb where I held increasing levels of responsibility becoming Vice President for the Clinical 发现 肿瘤学 & 免疫学 and Clinical Biomarkers groups. 

I joined AstraZeneca in 2010 as Head of 肿瘤学 in the IMED Biotech Unit and subsequently as Senior Vice President of Early 肿瘤学 R&D before taking up my current position leading 肿瘤学 R&D在2021年. 加入公司以来, I have played a part in bringing seven new medicines to patients in many countries around the world.

A critical focus for me in the drug development process is ensuring quality target selection and engagement and selecting the right patients for treatment. This has led to the successful development of several novel treatments and I am proud to have played a part in their development, together with a great team at AstraZeneca. I am also passionate about developing the next generation of scientists and on improving diversity via personal mentorship. 

除了我在澳门在线赌城娱乐的角色, I serve on the American Association for Cancer Research Board of Directors, the Institute of Cancer Research Scientific Advisory Board and the European Association of Cancer Research Advisory Council.


Academy of Medical Sciences (AMS) Fellowship, 2018

Institute of Cancer Research Honorary degree (Doctor of Science, Medicine), 2017

Scrip 奖, Best licensing deal of the year, 2013

电流的作用

肿瘤学执行副总裁&D

2010-2015

发现, early development and patient selection strategy for osimertinib, the fastest ever developed drug from first patient dosed to approval in 2 years 8 months

2010-2014

Early development and patient selection strategy for olaparib, AstraZeneca’s first DDR medicine

2010

Appointed to lead AstraZeneca IMED 肿瘤学

  特色的出版物

Imaging the Effects of Vascular-Targeting Agents. In Vascular Targeted Therapies in 肿瘤学

加尔布雷斯,年代.M. Imaging the Effects of Vascular-Targeting Agents. In Vascular Targeted Therapies in 肿瘤学.  D.W. 韦利·西曼主编 & 儿子,伦敦,277-304,2005.

Reproducibility of dynamic contrast-enhanced MRI in human muscle and tumors: comparison of quantitative and semi-quantitative analysis

加尔布雷斯年代.M.M室.A.泰勒·N.J., Rustin G.J.、本岑S.斯特灵J.J.帕德哈尼A.R.  核磁共振生物医学. 2002 Apr; 15 (2): 132-42

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